As Arthrosamid® works to cushion the joint, it can reduce your pain, decrease stiffness, and help movement.1,6-9 The hydrogel itself does not degrade and therefore it provides long-acting relief, improving your quality of life.¹ In clinical trials, patients reported a significant reduction in their pain symptoms by week 4 after their injection and, unlike other injectable treatments, the average level of reduction was maintained at the 3-year follow up period.10

† WOMAC or The Western Ontario and McMaster Universities Osteoarthritis Index is a measure of symptoms and physical disability. LSMeans are modelled/estimated means. The estimated means are using data from the other visits and also the covariates.

When will I begin to feel less pain?

You are likely to feel some pain relief within 24 hours; however, it can take 4 to 12 weeks to feel the maximum benefit. Clinical data shows that most patients start to feel an effect within a few weeks.1

When can I go back to normal activity?

You should avoid any strenuous weight-bearing activities (e.g. running, tennis or long walks) during the first few days after your injection. Your doctor will be able to advise you on how to slowly introduce more activity.

Do I need to tell any healthcare providers about my treatment?

If in the future you require a major surgical or dental procedure, you should tell your treating physician that you have an Arthrosamid® implant in your knee to ensure an accurate medical assessment.

How long will the treatment last?

The hydrogel making up the injection will not degrade, and therefore will provide long-lasting relief. So far, most patients have reported a significant reduction in their pain 4 weeks after their injection, and the average level of reduction was maintained at the 3-year follow-up period.5

What are the side effects?

In a number of clinical trials with Arthrosamid®, there were no serious side effects related to the hydrogel. The most commonly reported side effects were mild to moderate injection site pain and swelling, which were generally transient in nature. The overall safety profile of the hydrogel has been established over the last 20 years with its use for various indications in the body.

Is Arthrosamid® right for me?

Arthrosamid® is approved for the symptomatic treatment of knee osteoarthritis so any patient with this condition may be suitable. Over the last 10 years many patients have benefitted from treatment with the hydrogel in Arthrosamid®. However treatment with Arthrosamid® may not be suitable for everyone. Your doctor is the best person to advise you, but situations where you should not use Arthrosamid® (contraindications) include*:

• If you have an infection at or near the injection site
• If you have haemophilia or take anticoagulant treatment
• If you have had a knee arthroscopy within the past 6 months

Additionally, your doctor may advise you not to have treatment with Arthrosamid® if your diabetes is poorly controlled, you are having major dental work, or you have been diagnosed with an autoimmune disorder, (such as Multiple Sclerosis, Addison’s, or Coeliac disease). If you are under 18, pregnant, breastfeeding, or have a foreign body in your knee, your doctor may advise against the injection. This is because the safety and effectiveness of Arthrosamid® has not yet been established in these groups.

How does Arthrosamid® differ from other injectable treatments?

Arthrosamid® is different from the viscosupplement injections for the knee such as hyaluronic acid (HA), platelet rich plasma (PRP) and
regenerative stem cell therapy. Unlike these treatments, Arthrosamid® is a non degradable hydrogel which means it has the properties to lubricate and cushion for longer. Unlike the other treatments, Arthrosamid® also has the ability to become an integrated part of the soft synovial tissue in the joint capsule which may lead to longer lasting pain relief.5